The last time Port Vale met Stevenage, The Valiants came away empty handed, losing 2-0 away from home at Broadhall Way back in September.
Striker Danny Newton fired home from a tight angle after 22 minutes following Ben Kennedy's surging forward run.
In the second half, Jonathan Smith sealed the game with a curled effort into the top corner after 54 minutes.
Vale were managerless on the day, with Neil Aspin being unveiled as the club's new manager only 4 days later.
The Valiants may feel more confident at home though, as they beat The Boro in the last encounter at Vale Park in the FA Cup, back in 2016, Remie Streete the scorer on that day.
Surprisingly though, these two teams have only met 8 times in the entire history of both clubs, with the first encounter only taking place in 2009 in the FA Cup, whcih ended in a 1-1 draw.
Since then, Vale have managed 2 wins, 2 draws, and 3 losses against The Boro.