Vale make the short trip to Gresty Road to face Crewe Alexandra in Sky Bet League Two on Monday afternoon, but what happened when the sides last faced each other?
The last A500 derby was back in November of 2017 as the Valiants sealed their progression in the Checkatrade Trophy at Vale Park. Neil Aspin's men got off to a flying start, with Chris Regis opening the scoring just three minutes into his debut.
Anton Forrester doubled the advantage five minutes later with an expertly taken strike, but Lewis Reilly pulled one back before the break to bring David Artell's back in contention.
Following the restart, the goals continued to flow and it was Vale who struck next to restore their two-goal cushion. Adam Yates picked out Billy Reeves with a perfectly placed cross and the midfielder poked the ball beyond Ben Garratt.
Reilly then secured a brace to make it 3-2, but the day belonged to the home side and they wrapped up proceedings in fine style late on. After picking up the ball on the halfway line, Cristian Montano raced through on goal before planting a finish past the goalkeeper.
Our last league meeting came in August of this season, but it was Crewe who came out on top in Burslem. Chris Dagnall scored the only goal of the game on 30 minutes, and following Michael Tonge's 34th-minute dismissal, ten-man Vale were unable to mount a comeback.
You have to rewind to August of 2015 to find the last fixture between the two teams at Gresty Road, but the local rivalry failed to produce anything spectacular on that occassion and a goalless draw was played out in League One.