Bolton are the favourites at 3/4 to pick up all three points , whilst the draw is at 13/5.
Gary Madine is joint favourite with Adam Le Fondre to open the scoring in the game and can both be backed at 9/2.
JJ Hooper is the favourite for Vale at 15/2 and behind him is Rigino Cicilia at 8/1.
Last time the Valiants beat Bolton, Vale came away with a 2-1 win back in 1988 and the odds of a same score again are 14/1.
Also, if you expect Vale to keep a clean sheet in the game, then you can get Vale to win to nil at 15/2 or both teams not to score at 5/6.
Please remember that all odds are subject to change and for more information then please head to www.skybet.com.